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Vitamin D is well known in its endogenous form: the skin is able to synthesize a considerable amount when it is exposed to sunlight for a long period.
As a dietary supplement it is a liposoluble vitamin absorbed slowly and it has up to 40% bio availability in cholecalciferol, vitamin D3. It is metabolised in the liver and the kidneys in 1.25 – dehydrovitamins, e.g. 25OHD to be activated. It is an excellent source of vitamin D.
Healthcare specialists are well aware of the way it works and how important it is for good health.
It ensures bone minerals and maintains calcium homeostasy. Other beneficial effects have been observed when the cholecalciferol dose is properly administered. The most recent scientific journals have brought to light that a low rate of 25OHD, < 20ng/mol, is linked to chronic illnesses, for example: diabetes, bone disease and a dozen different types of cancer: breast, prostate, kidney, bowel… as well as cardiovascular diseases.
Those who live in places where there is little or no exposure to sunlight are most likely subject to vitamin D3 deficiency. According to specialists this affects around 1 billion people . For those who are the most vulnerable, such as old people as synthesis of 25OHD decreases 4-fold because of skin ageing.
Maintaining the good rate of 25OHD strengthens bones and the immune system, lowers risk of fractures, cardiovascular diseases and diabetes.
Alter Med Rev. 2005 Jun; 10(2) :94-111. Benefits and requirements of vitamin D for optmia health : revview. Grant WB1, Holick MF
 Volume 29, Issue 10, October 2008, Pages 815-820 La Revue de Medeccine Interne V.I Mistrettaa, P. Delanayeb, J-P Chapellea, J.C. Souberbiellec, E. Cavaliera
 Pan Afr Med J. 2014; 17: 152 Dosage de la 25 OH vitamine D: expérience du laboratoire central de biochimie clinique du Centre Hospitalier Ibn Sina Najat Handor,1,& Sanae Elalami,1 Mounya Bouabdellah,1 Abdelatif Srifi,1 Hicham Esselmani,1 Laila Benchekroun,1 et Layachi Chabraoui1
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